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折扣/货期| 货号：GTX79679 | 规格：100μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Prorenin antibody [4B5-E3] (Inhibitory)
别名:
HNFJ2,REN,renin,Renin,Prorenin
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, Neutralizing/Inhibition, WB
靶标/特异性:
Recognises amino acid residues 3-43 (MARLGPEWSQPMKR) of the prosegment of prorenin.
同种型:
IgG2b
免疫原:
Recombinant full length wild-type human protein (Glycosylated).
克隆性:
Monoclonal
克隆号:
4B5-E3
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
45
产品形式:
Liquid
存储溶液:
50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
生产商:
GeneTex
功能与背景:
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
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