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折扣/货期| 货号：19-728 | 规格：100 uL | 目录价：￥7651.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PSMF1 Antibody
别名:
PSMF1, proteasome (prosome, macropain) inhibitor subunit 1 (PI31), PI31, RP4-545L17.1, proteasome inhibitor hP131 subunit, proteasome inhibitor subunit 1
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
WB,IHC,IF
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
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