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折扣/货期| 货号：XW-7826 | 规格：0.05 mg | 目录价：￥11196.9 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PTPN1 Antibody
别名:
PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B, Tyrosineprotein phosphatase nonreceptor type 1
反应种属:
Human,Rat
宿主来源:
Chicken
实验应用:
WB
克隆性:
Polyclonal
纯化方式:
Immunoaffinity Purified
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
PTPN1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Phosphate-Buffered Saline. No preservatives added.
产地:
美国
生产商:
Prosci
功能与背景:
FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
Accession #:
NP_002818.1
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