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折扣/货期| 货号：SIH-306-50MG | 规格：50 mg | 目录价：￥7545.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Pyr3
别名:
Ethyl 1-{4-[(2,3,3-trichloroacryloyl)amino]phenyl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
产品描述:
TRPC3 Channel blocker
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
456.63
产品形式:
White Solid
产地:
加拿大
功能与背景:
Pyr3, a novel pyrazole, selectively inhibits TRPC3 channels. In B lymphocytes, Pyr3 eliminated the B cell receptor-induced Ca2+ oscillation regulated by TRPC3-mediated Ca2+ influx. In the cardiac system, Pyr3 attenuates activation of nuclear factor of activated T cells and hypertrophic growth in myocytes and pressure overloaded-induced hypertrophy in vivo (1).
纯度:
>98%
来源:
Synthetic
CAS号:
1160514-60-2
分子式:
C16H11Cl3F3N3O3
溶解度:
Soluble to 100 mM in DMSO
PubChem CID:
56964346
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