| 货号:AG-CP3-0006-3001 | 规格:3 x 1 mg | 目录价:¥5400 |
| 货号:AG-CP3-0006-M001 | 规格:1 mg | 目录价:¥1980 |
| 货号:AG-CP3-0006-M005 | 规格:5 mg | 目录价:¥7800 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Q-VD-OPh
别名:
Q-Val-Asp-OPh; pan-Caspase Inhibitor; N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone
产品描述:
Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
BI
预期分子量:
513.5
产品形式:
solid
产地:
瑞士
纯度:
>95% (TLC)
生物活性:
The IC50 range for caspases -1, -3, -8, -9, -10, and -12 is 25-400 nM.
CAS号:
1135695-98-5 (anhydrous)
分子式:
C26H25F2N3O6
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