| 货号:44704-1 mg | 规格:1 mg | 目录价:¥335 |
| 货号:44704-10 mg | 规格:10 mg | 目录价:¥2345 |
| 货号:44704-25 mg | 规格:25 mg | 目录价:¥3765.4 |
| 货号:44704-5 mg | 规格:5 mg | 目录价:¥1420.4 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MPI-0479605
产品描述:
An Mps1 inhibitor (IC50 = 1.8 nM); selective for Mps1 over a panel of 79 kinases at 500 nM; induces time-dependent degradation of cyclin B and securin and decreases phosphorylation of Mad3, resulting in failed cytokinesis in nocodazole-arrested HeLa cells; induces cell cycle arrest at the G2/M phase in HCT116 cells, which express p53wt, and COLO 205 cells, which express p53mut, at 1 µM; reduces tumor volume in an HCT116 mouse xenograft model at 30 to 150 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
407.522
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1246529-32-7
分子式:
C22H29N7O
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