RAC1 Antibody-单抗-深圳欣博盛生物科技有限公司

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RAC1 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V7332-100UG

规格：100 ug

目录价：￥6652.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

RAC1 Antibody

产品描述:

Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Rac1 has been demonstrated to play a critical role in tumor progression of human colorectal adenocarcinoma cells. In one study, overexpression of Rac1 accelerated the tumorigenic process, whereas Rac1 inhibition completed suppressed tumor formation.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC-P

同种型:

Mouse IgG1

免疫原:

Full length recombinant human protein was used as the immunogen for this RAC1 antibody.

克隆性:

Monoclonal (mouse origin)