| 货号:SIH-577-250MG | 规格:250 mg | 目录价:¥3614.4 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Rasagiline mesylate
别名:
(1R)-2,3-Dihydro-N-2-propynyl-1H-inden-1-amine, methanesulfonate; TVP-1012; Azilect
产品描述:
MAO inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
267.3
产品形式:
White crystalline powder
产地:
加拿大
功能与背景:
Potent, irreversible monoamine oxidase (MAO) inhibitor selective for MAO-B (IC50=4.43 nM) over MAO-A (IC50=412 nM) (1). Parkinson’s disease therapeutic (2). Displays neuroprotective and neurorestorative properties in a Parkinson’s disease zebrafish model (3). Prevents α-synuclein-induced dopaminergic neuronal death and rescues TrkB neurotrophic signaling (4). Enhances BDNF levels and is neuroprotective in Parkinson’s disease models (5).
纯度:
>99% (HPLC); NMR (Conforms)
来源:
Synthetic
CAS号:
161735-79-1
分子式:
C12H13N • CH3SO3H
溶解度:
May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml); Ethanol (30 mg/ml)
PubChem CID:
3052775
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