Recombinant CD163 Antibody-单抗-深圳欣博盛生物科技有限公司

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Recombinant CD163 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V8757SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant CD163 Antibody

产品描述:

CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P

同种型:

Rabbit IgG

免疫原:

A portion of amino acids 1056-1156 from the human protein was used as the immunogen for the recombinant CD163 antibody.

克隆性:

Recombinant Rabbit Monoclonal