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折扣/货期| 货号：V4435SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant CDH1 Antibody / E-Cadherin
产品描述:
Recognizes a protein of 120-80kDa, identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as Beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
Mouse IgG1, kappa
免疫原:
Recombinant full-length human protein was used as the immunogen for the recombinant CDH1 antibody.
克隆性:
Recombinant Mouse Monoclonal
克隆号:
rCDH1/7352
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the recombinant CDH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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