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折扣/货期| 货号：350-04-100UG | 规格：100 ug | 目录价：￥1227 |
| 货号：350-04-01M | 规格：2 x 500 ug | 目录价：￥6067 |
| 货号：350-04-500UG | 规格：500 ug | 目录价：￥3204 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human ApoE4
别名:
Apolipoprotein E4
产品描述:
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in the liver and brain, and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. Its interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer's disease. Recombinant Human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
促销活动
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