| 货号:120-06-100UG | 规格:100 ug | 目录价:¥22960 |
| 货号:120-06-10UG | 规格:10 ug | 目录价:¥2941 |
| 货号:120-06-01M | 规格:2 x 500 ug | 目录价:¥90610 |
| 货号:120-06-250UG | 规格:250 ug | 目录价:¥40148 |
| 货号:120-06-2UG | 规格:2 ug | 目录价:¥1207 |
| 货号:120-06-500UG | 规格:500 ug | 目录价:¥59648 |
| 货号:120-06-50UG | 规格:50 ug | 目录价:¥13761 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human BMP-6
别名:
Bone Morphogenetic Protein-6, VGR, VG-1-related protein
产品描述:
TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity, and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown. The mature and functional form of BMP-6 is a homodimer of two identical 139 amino acid polypeptide chains linked by a single disulfide bond. Each monomer is expressed as the C-terminal part of a precursor polypeptide, which contains a 20 amino acid signal peptide and a 354 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant Human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor.
宿主来源:
HEK293 cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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