Recombinant Human DKK-1-其他重组蛋白-深圳欣博盛生物科技有限公司

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Recombinant Human DKK-1

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：120-30-100UG	规格：100 ug	目录价：￥22960
货号：120-30-10UG	规格：10 ug	目录价：￥2941
货号：120-30-1MG	规格：1 mg	目录价：￥91944
货号：120-30-250UG	规格：250 ug	目录价：￥40148
货号：120-30-2UG	规格：2 ug	目录价：￥1207
货号：120-30-500UG	规格：500 ug	目录价：￥59648
货号：120-30-50UG	规格：50 ug	目录价：￥13761

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human DKK-1

别名:

Dickkopf-related protein-1, Dickkopf-1, SK

产品描述:

DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head-forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play important regulatory roles in the Wnt/beta-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/beta-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/beta-catenin signaling cascade. It has been suggested that by inhibiting Wnt/beta-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Mature human DKK-1 expressed in HEK293 cells is a 35-40 kDa glycoprotein containing 235 amino acid residues. The calculated molecular weight of Recombinant Human DKK-1 expressed in HEK293 cells is 25.8 kDa.

宿主来源:

HEK293 cells

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech