Recombinant Human EGF-L7-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human EGF-L7

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：100-61-100UG	规格：100 ug	目录价：￥13295
货号：100-61-10UG	规格：10 ug	目录价：￥2956
货号：100-61-01M	规格：2 x 500 ug	目录价：￥52532
货号：100-61-250UG	规格：250 ug	目录价：￥23263
货号：100-61-2UG	规格：2 ug	目录价：￥1213
货号：100-61-500UG	规格：500 ug	目录价：￥34575
货号：100-61-50UG	规格：50 ug	目录价：￥7986

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human EGF-L7

别名:

Epidermal growth factor-like protein 7, MEGF7, Multiple EGF-like domains protein 7, NOTCH4-like protein, VE-statin, Zneu1

产品描述:

EGF-L7 (Epidermal growth factor-like protein 7, Multiple EGF-like domains protein 7, VE-statin) is a multi-domain protein containing two EGF-like domains and one EMI domain. It is expressed almost exclusively in endothelial cells and functions to promote normal development of the vascular system, particularly tubulogenesis. EGF-L7 is capable of antagonistic binding to Notch receptors, resulting in the inhibition of Notch signaling in HUVEC and neural stem cells. In research models inducing hypoxia and subsequent reoxygenation (H/R), EGF-L7 can inhibit ICAM-1 expression and enhance the inhibition of NF-kappaB activation. Additionally, EGF-L7 can chemoattract endothelial cells and bind to the extracellular matrix. The overexpression of EGF-L7 is observed in various cancers, and is generally correlated with increased metastasis and a poor prognosis. Recombinant Human EGF-L7 is a 27.4 kDa protein containing 251 amino acid residues.

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech