Recombinant Human p16-INK4a-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human p16-INK4a

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：110-02-100UG	规格：100 ug	目录价：￥15500
货号：110-02-01M	规格：10 x 100 ug	目录价：￥68282
货号：110-02-20UG	规格：20 ug	目录价：￥3288
货号：110-02-500	规格：5 x 100 ug	目录价：￥44308
货号：110-02-5UG	规格：5 ug	目录价：￥1213

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human p16-INK4a

别名:

Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16INK4A, p16-INK4, Multiple tumor suppressor 1, MTS-1

产品描述:

p16-INK4a is a nuclear protein that regulates the cell cycle by inhibiting cyclin-dependent kinase-4 (CDK4) and CDK6. p16-INK4a inhibits CDK activity by binding to the CDK molecules in a manner that interferes with their ability to interact with cyclin D. This activity has the effect of suppressing tumor formation and growth, and of inducing replicative senescence in various normal cells, including stem cells. The expression of p16-INK4a steadily increases with age, and tends to accumulate in stem cell compartments. The deletion, rearrangement, or mutation of the p16-INK4a gene is frequently found in melanomas, as well as in certain other types of cancer. Recombinant Human p16-INK4a is a 16.5 kDa protein containing 156 amino acid residues. Kim, W.Y. and Sharpless, N.E. (2006)Cell 127(2):265-75.

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech