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折扣/货期| 货号：140-04-100UG | 规格：100 ug | 目录价：￥23072 |
| 货号：140-04-10UG | 规格：10 ug | 目录价：￥2956 |
| 货号：140-04-1MG | 规格：1 mg | 目录价：￥92394 |
| 货号：140-04-250UG | 规格：250 ug | 目录价：￥40345 |
| 货号：140-04-2UG | 规格：2 ug | 目录价：￥1213 |
| 货号：140-04-500UG | 规格：500 ug | 目录价：￥59940 |
| 货号：140-04-50UG | 规格：50 ug | 目录价：￥13828 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human PAI-1
别名:
Plasminogen Activator Inhibitor-1, Serpin E1
产品描述:
Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, but is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity-related factors, such as TNFalpha, glucose, insulin, and very-low-density lipoprotein. The obesity-related elevation of PAI-1 levels, along with the consequential deficiency in plasminogen activators, can lead directly to increased risk of thrombosis and other coronary diseases. Accordingly, PAI-1 has been implicated as an important molecular link between obesity and coronary disease. PAI-1 can also specifically bind vitronectin (VTN) to form a stable active complex with an increased circulatory half-life relative to free PAI-1. Recombinant Human PAI-1 is a 42.7 kDa protein containing 379 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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