| 货号:140-07-100UG | 规格:100 ug | 目录价:¥12031 |
| 货号:140-07-1MG | 规格:1 mg | 目录价:¥53305 |
| 货号:140-07-250UG | 规格:250 ug | 目录价:¥23263 |
| 货号:140-07-25UG | 规格:25 ug | 目录价:¥3018 |
| 货号:140-07-500UG | 规格:500 ug | 目录价:¥34575 |
| 货号:140-07-5UG | 规格:5 ug | 目录价:¥1213 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human sDLL-4
别名:
soluble DLL-4, Delta-like protein 4, Drosophila Delta homolog 4
产品描述:
Human sDLL-4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I transmembrane proteins that serve as ligands for Notch receptors. DLL-4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL-4 gene in mice resulted in severe vascular defects and death before birth. Up-regulation of DLL-4 expression has been implicated in the vascular development of certain tumors. The human DLL-4 gene consists of a 503 amino acid extracellular domain with one DSL domain, eight EGF-like repeats, a 21 amino acid transmembrane domain, and a 135 amino acid cytoplasmic domain. Recombinant Human sDLL-4 is a 54.3 kDa glycoprotein containing 498 amino acid residues.
宿主来源:
HEK293 cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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