官网链接
折扣/货期| 货号：300-28G-100UG | 规格：100 ug | 目录价：￥13295 |
| 货号：300-28G-10UG | 规格：10 ug | 目录价：￥2956 |
| 货号：300-28G-1MG | 规格：1 mg | 目录价：￥53305 |
| 货号：300-28G-250UG | 规格：250 ug | 目录价：￥23263 |
| 货号：300-28G-2UG | 规格：2 ug | 目录价：￥1213 |
| 货号：300-28G-500UG | 规格：500 ug | 目录价：￥34575 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human SDF-1gamma (CXCL12)
别名:
Stromal‐Cell Derived Factor‐1, PBSF
产品描述:
The SDF‐1 proteins are stromal‐derived CXC chemokines that signal primarily through the CXCR4 receptor. SDF‐1 proteins exert chemotactic activity over a broad range of immune system cell types and may also be involved in other processes including metastasis of certain cancers, inflammation, and angiogenesis. Additionally, SDF‐1 can suppress HIV entry into cells expressing the CXCR4 receptor. Five isomers of SDF‐1 have been found with SDF‐1alpha being the predominant form, expressing in a wide range of cell types. The SDF‐1gamma isoform is distinctive in that it contains a highly basic C‐terminal region, which presumably is the reason for its high binding affinity to gylcosaminoglycans (GAG) and heparin sulfate (HS). Consequently, most of SDF‐1gamma exists in a cell‐ and membrane‐bound form, which confers greater stability compared to other isoforms via increased resistance to proteolytic degradation. SDF‐1gamma binds with reduced affinity to the CXCR4 receptor when compared to the alpha and beta isoforms, but because of its increased stability can, over time, exert equal or greater activity when compared to other SDF‐1 isoforms. SDF‐1gamma expression has been found primarily in the heart (human and mouse) and in the brain and central nervous system (rat). Recombinant Human SDF‐1gamma (CXCL12) is an 11.6 kDa protein containing 98 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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