Recombinant Human sIL-12 Receptor Beta-2 Fc-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Recombinant Human sIL-12 Receptor Beta-2 Fc

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：200-12RB-2-100UG	规格：100 ug	目录价：￥询价
货号：200-12RB-2-1MG	规格：1 mg	目录价：￥询价
货号：200-12RB-2-20UG	规格：20 ug	目录价：￥询价
货号：200-12RB-2-250UG	规格：250 ug	目录价：￥询价
货号：200-12RB-2-500UG	规格：500 ug	目录价：￥询价

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human sIL-12 Receptor Beta-2 Fc

产品描述:

The IL-12 structurally related family of heterodimeric proteins plays an important role in activating, regulating, and modulating the immune response. This family of proteins transmits its activity through receptors, which, when stimulated by ligand binding, generally activate JAK proteins that subsequently phosphorylate STAT transcription factors. IL-12R β-2 is a single pass membrane protein expressed primarily on certain naive T cells. By itself, IL-12R β-2 appears to exert minimal activity but when paired with IL-12R β-1, forms a high affinity IL-12 receptor. IL-12R β-2 can also pair with gp130 to form a high affinity receptor for IL-35. Recombinant Human IL-12 Receptor β-2 Fc has a calculated molecular weight of 94.9 kDa, and contains 839 amino acid residues, which consists of the extracellular domain of IL-12R β-2 fused to the Fc portion of human IgG and contains a C-terminal His-tag. Due to glycosylation, it migrates at an approximate molecular weight of 116 kDa, under reducing conditions.

宿主来源:

CHO cells

保存温度:

Minus 20C

运输温度:

Room Temperature

预期分子量:

94.9

产品形式:

Standard

产地:

美国