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折扣/货期| 货号：140-14-100UG | 规格：100 ug | 目录价：￥2956 |
| 货号：140-14-01M | 规格：2 x 500 ug | 目录价：￥19265 |
| 货号：140-14-20UG | 规格：20 ug | 目录价：￥1213 |
| 货号：140-14-250UG | 规格：250 ug | 目录价：￥8529 |
| 货号：140-14-500UG | 规格：500 ug | 目录价：￥12677 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human/Murine/Rat Thymosin-beta4
别名:
Tbeta-4, Hematopoietic system regulatory peptide, Seraspenide, TMSB4X, TB4X, TMSB4
产品描述:
Thymosin-beta4 is a small, actin-sequestering protein belonging to the thymosin-beta family that is found at high concentrations within the spleen, thymus, and peritoneal macrophages, where it is most notably responsible for the organization of cytoskeletal structure. In mammalian tissues, this protein acts as a modulator for the polymerization/depolymerization of actin through the formation of a 1:1 complex with the monomer G (globular)-actin, and inhibits actin's polymerization to form F (filamentous) actin, which together with other proteins binds microfilaments to construct the cytoskeleton. Commonly found at significant quantities within the brain, lungs, liver, kidneys, testes, and heart, thymosin-beta4 has also been shown to be synthesized by cells unrelated to the reticuloendothelial system, such as myoblasts and fibroblasts, and expressed at irregular levels by several hemopoietic cell lines, malignant lymphoid cells and myeloma cells. In addition to regulating actin polymerization, research has also found thymosin-beta4 to stimulate the secretion of hypothalamic luteinizing hormone-releasing hormone and luteinizing hormone, inhibit the migration of peritoneal macrophages, induce phenotypic changes in T cell lines during early host defense mechanisms, and inhibit the progression of hematopoietic pluripotent stem cells into the S-phase. Recombinant Human/Murine/Rat Thymosin-beta4 is a 5.2 kDa glycoprotein containing 45 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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