Recombinant Insulin Receptor alpha Antibody-单抗-深圳欣博盛生物科技有限公司

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Recombinant Insulin Receptor alpha Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V3586-100UG	规格：100 ug	目录价：￥6652.1
货号：V3586-20UG	规格：20 ug	目录价：￥3082.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Insulin Receptor alpha Antibody

产品描述:

The insulin receptor (INSR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide-linked to a transmembrane segment. The insulin ligand binds to the INSR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to INSR induces phosphorylation of intra-cellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Type 1 diabetes is an autoimmune condition of the endocrine pancreas that results in destruction of insulin secreting cells and a progressive loss in insulin-sensitive glucose uptake by cells.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

Rabbit IgG, kappa

免疫原:

A recombinant partial protein from the extracellular region of the protein was used as the immunogen for the recombinant Insulin Receptor alpha antibody.

克隆性:

Recombinant Rabbit Monoclonal

克隆号:

INSR/2277R

纯化方式:

Protein A affinity chromatography

保存温度:

Store the recombinant Insulin Receptor alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

产品形式:

Purified

存储溶液:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide