Recombinant MTAP Antibody / S-methyl-5'-thioadenosine phosphorylase-单抗-深圳欣博盛生物科技有限公司

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Recombinant MTAP Antibody / S-methyl-5'-thioadenosine phosphorylase

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V7439SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant MTAP Antibody / S-methyl-5'-thioadenosine phosphorylase

产品描述:

Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, WB, IHC-P

同种型:

Rabbit IgG, kappa

免疫原:

A portion of amino acids 97-196 from the human protein was used as the immunogen for the recombinant MTAP antibody.

克隆性:

Recombinant Rabbit Monoclonal