深圳欣博盛生物科技有限公司 a1

RGB-286638
货号:29499-100 mg 规格:100 mg 目录价:¥1273
货号:29499-250 mg 规格:250 mg 目录价:¥2787
货号:29499-500 mg 规格:500 mg 目录价:¥4958
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RGB-286638
产品描述:
A multi-kinase inhibitor; inhibits a variety of kinases, including CDK2-7 and CDK9, FMS, JAK2, c-Src, GSK3β, TAK1, JNK1A1, JNK1A2, AMPK, and MEK1 (IC50s = 1-55 nM); inhibits proliferation of multiple myeloma cancer cell lines endogenously expressing mutant and wild-type p53 (EC50s = 20-70 nM), as well as patient-derived multiple myeloma cells at 50 and 100 nM; induces G1/S and G2/M cell cycle arrest and apoptosis of MM.1S human multiple myeloma cells at 50 nM; decreases tumor growth in an MM.1S mouse xenograft model at 30 and 40 mg/kg per day for 14 days
保存温度:
-20
运输温度:
-20
预期分子量:
545.63298
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
784210-88-4
分子式:
C29H35N7O4
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