| 货号:71742-10 mg | 规格:10 mg | 目录价:¥911 |
| 货号:71742-100 mg | 规格:100 mg | 目录价:¥6285 |
| 货号:71742-5 mg | 规格:5 mg | 目录价:¥482 |
| 货号:71742-50 mg | 规格:50 mg | 目录价:¥3591 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Rosiglitazone (potassium salt)
产品描述:
A PPARγ agonist; activates PPARγ1 and PPARγ2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
395.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
316371-84-3
分子式:
C18H18N3O3S • K
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