深圳欣博盛生物科技有限公司 a1

Rosiglitazone
货号:71740-10 mg 规格:10 mg 目录价:¥448
货号:71740-100 mg 规格:100 mg 目录价:¥2576
货号:71740-25 mg 规格:25 mg 目录价:¥882
货号:71740-50 mg 规格:50 mg 目录价:¥1526
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Rosiglitazone
别名:
BRL 49653
产品描述:
A PPARγ agonist; activates PPARγ1 and PPARγ2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
357.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
122320-73-4
分子式:
C18H19N3O3S
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询