| 货号:GTX13826 | 规格:100μl | 目录价:¥6100 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RPE65 antibody [401.8B11.3D9]
别名:
retinoid isomerohydrolase RPE65
反应种属:
Bovine, Chicken, Dog, Human, Mouse, Pig, Rat, Xenopus
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-Fr, IHC-P, MS, WB
同种型:
IgG1
免疫原:
Bovine RPE65 microsomal membrane proteins. [UniProt# Q28175]
克隆性:
Monoclonal
克隆号:
401.8B11.3D9
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
61
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
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