| 货号:GTX642048 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX642048-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RPS6 (phospho Ser240/Ser244) antibody [HL3824]
别名:
ribosomal protein S6 , S6
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody detects RPS6 protein when dually phosphorylated at Ser240 and Ser244, and it also reacts with RPS6 protein when singly phosphorylated at Ser240 and Ser244.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Ser240/Ser244 of human RPS6. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3824
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
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