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折扣/货期| 货号：21546-10 mg | 规格：10 mg | 目录价：￥1702 |
| 货号：21546-25 mg | 规格：25 mg | 目录价：￥3980 |
| 货号：21546-5 mg | 规格：5 mg | 目录价：￥925 |
| 货号：21546-50 mg | 规格：50 mg | 目录价：￥7477 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Safinamide (mesylate)
别名:
EMD 1195686|FCE 26743|NW-1015|PNU-151774E
产品描述:
An inhibitor of MAO-B (IC50 = ~0.1 μM); selective for MAO-B over MAO-A (IC50 = >10 μM); inhibits radioligand binding to sodium channel binding site 2, sigma-1, and sigma-2 receptors in rat brain membranes (IC50s = 8.2, 0.019, and 1.59 μM, respectively); inhibits high voltage-activated calcium currents and depolarization-induced tetrodotoxin-sensitive fast sodium currents in rat hippocampal neurons; inhibits veratrine-induced glutamate release in rat hippocampal slices (IC50 = 56 μM); inhibits maximal electroshock-induced tonic extension seizures in mice and rats (ED50s = 8 and 11.8 mg/kg, p.o.) as well as maximal seizures induced by bicuculline, picrotoxin, 3-mercaptopropionic acid, and strychnine in mice (ED50s = 26.9, 60.6, 21.5, and 104.1 mg/kg, p.o., respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
302.29
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
202825-46-5
分子式:
C17H19FN2O2 • CH3SO3H
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