SARS-CoV-2 (COVID-19) NSP1 Recombinant Protein-重组病毒蛋白-深圳欣博盛生物科技有限公司

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SARS-CoV-2 (COVID-19) NSP1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：10-416

规格：0.1 mg

目录价：￥9038.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SARS-CoV-2 (COVID-19) NSP1 Recombinant Protein

别名:

SARS-CoV 2 nsp1,SARS-CoV 2 Leader protein

表达系统:

E. coli

保存温度:

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week. Store at -20 to -80 ˚C for twelve months from the date of receipt.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.

产地:

美国

生产商:

Prosci

功能与背景:

The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.

纯度:

>85% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.

Accession #:

YP_009725297.1

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