SARS-CoV-2 (COVID-19) South African variant (B.1.351) S RBD (K417N, E484K, N501Y) Recombinant Protein-重组病毒蛋白-深圳欣博盛生物科技有限公司

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SARS-CoV-2 (COVID-19) South African variant (B.1.351) S RBD (K417N, E484K, N501Y) Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：11-065

规格：0.1 mg

目录价：￥10126.35

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SARS-CoV-2 (COVID-19) South African variant (B.1.351) S RBD (K417N, E484K, N501Y) Recombinant Protein

别名:

2019-nCov RBD Protein,2019-nCoV Spike RBD Protein

表达系统:

Mammalian Cells

保存温度:

Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 ˚C for one week .Store at -20 to -80 ˚C for twelve months from the date of receipt.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.

产地:

美国

生产商:

Prosci

功能与背景:

Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

纯度:

>90% as determined by SDS-PAGE

Accession #:

YP_009724390.1(K417N, E484K, N501Y)

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