SARS-CoV-2 (COVID-19) Spike S1 Recombinant Protein-重组病毒蛋白-深圳欣博盛生物科技有限公司

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SARS-CoV-2 (COVID-19) Spike S1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：21-805

规格：50 ug

目录价：￥6405.75

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SARS-CoV-2 (COVID-19) Spike S1 Recombinant Protein

别名:

2019-nCoV Spike Protein S1 (RBD); Spike Receptor Binding Domain

产品浓度:

1mg/ml after reconstitution.

表达系统:

HEK293 cells

保存温度:

Short Term StorageL: +4°C, Long Term Storage: -20°C, Handling Advice: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For maximum product recovery after thawing, centrifuge the vial before opening the cap. Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Lyophilized. Contains PBS.

产地:

美国

生产商:

Prosci

功能与背景:

SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins: the Spike (S) protein, Nucleocapsid (N) protein, Membrane/Matrix (M) protein and the Envelope (E) protein. The SARS Envelope (E) protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix (M) protein is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with SARS Spike (S) protein and the Nucleocapsid (N) protein. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms. The CoV Spike (S) protein assembles as trimer and plays the most important role in viral attachment, fusion and entry. It is composed of a short intracellular tail, a transmembrane anchor and a large ectodomain that consists of a receptor binding S1 subunit (RBD domain) and a membrane-fusing S2 subunit. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor angiotensin-converting enzyme 2 (ACE2) present at the surface of epithelial cells.

纯度:

≥95% (SDS-PAGE)

生物活性:

Binds to the human ACE2.

Accession #:

QHD43416.1

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