| 货号:RQ6299 | 规格:100 ug | 目录价:¥6921.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SARS-CoV-2 NSP2 Antibody
产品描述:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF1ab, the largest gene, contains overlapping open reading frames that encode polyproteins PP1ab and PP1a. The polyproteins are cleaved to yield 16 nonstructural proteins, NSP1-16. Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based on similarity to other coronaviruses, include the papain-like proteinase protein (NSP3), 3C-like proteinase (NSP5), RNA-dependent RNA polymerase (NSP12, RdRp), helicase (NSP13, HEL), endoRNAse (NSP15), 2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins. SARS-CoV-2 nonstructural proteins are responsible for viral transcription, replication, proteolytic processing, suppression of host immune responses and suppression of host gene expression. The RNA-dependent RNA polymerase is a target of antiviral therapies.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA
同种型:
Rabbit IgG
免疫原:
Amino acids AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDG
FMGRIRSVYPVASPNECNQggggQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQP
TSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLK were used as the immunogen for the SARS-CoV-2 NSP2 antibody.
FMGRIRSVYPVASPNECNQggggQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQP
TSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLK were used as the immunogen for the SARS-CoV-2 NSP2 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Affinity purified
保存温度:
After reconstitution, the SARS-CoV-2 NSP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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