Selenoprotein P antibody, N-term-多抗-深圳欣博盛生物科技有限公司

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Selenoprotein P antibody, N-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX45069

规格：50μg

目录价：￥6000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Selenoprotein P antibody, N-term

别名:

selenoprotein P , SELP , SEPP , SEPP1 , SeP

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

A synthetic peptide corresponding to a N-terminal region of Human Selenoprotein P.

克隆性:

Polyclonal

克隆号:

纯化方式:

Affinity Purified

偶联:

Unconjugated

产品浓度:

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 2% Sucrose, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2017]

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