官网链接
折扣/货期| 货号：CDX-S0088-M010 | 规格：10 mg | 目录价：￥896 |
| 货号：CDX-S0088-M050 | 规格：50 mg | 目录价：￥3556 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sertraline hydrochloride
别名:
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride; CP 51,974-1; Lustral; Seserine; Zoloft
产品描述:
Sertraline is a tetraline that inhibits monoamine transporters and acts as a potent highly selective serotonin reuptake inhibitor (SSRI), with affinity for the serotonin transporter (SERT), increasing availability of serotonin (5-hydroxytryptamine; 5-HT) in the brain and leading to antidepressant, anxiolytic and antiobsessional effects. Sertraline binds also to the dopamine transporter (DAT) and the sigma1 receptor (but not the sigma2 receptor) with 100-fold lower affinity. It acts as an antagonist of the sigma1 receptor, and is able to reverse sigma1 receptor-dependent actions of fluvoxamine, a potent agonist of the receptor, in vitro. Sertraline displays antiproliferative activity on human colorectal carcinoma cells.
宿主来源:
Synthetic.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
342.69
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
79559-97-0
分子式:
C17H17NCl2 . HCl
溶解度:
Soluble in DMSO (20mg/ml) or ethanol (10mg/ml).
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