官网链接
折扣/货期| 货号：CDX-S0078-M050 | 规格：50 mg | 目录价：￥1834 |
| 货号：CDX-S0078-M250 | 规格：250 mg | 目录价：￥7364 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sildenafil citrate
别名:
5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-one citrate salt; Actra-Rx; Edegra; Viagra; Tonafil; Apodefil; UK 92480
产品描述:
Potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. It inhibits PDE5 activity in isolated rabbit platelets with an IC50 value of 3.6nM (3nM in human corpus cavernosum) compared to inhibition of PDE1 and PDE3 activities (IC50s = 0.26 and 65µM, respectively). Inhibition of PDE5 enhances the relaxation of smooth muscle in a range of vascular tissues by prolonging the nitric oxide/cGMP-mediated activation of cGMP-dependent protein kinase. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. The citrate salt has superior water solubility and pharmacokinetics compared to the base salt of sildenafil.
宿主来源:
Synthetic.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
474.6 . 192.1
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
171599-83-0
分子式:
C22H30N6O4S . C6H8O7
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