SHP1 (internal region) blocking peptide-单抗-深圳欣博盛生物科技有限公司

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SHP1 (internal region) blocking peptide

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX89108-PEP

规格：100μl

目录价：￥3200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SHP1 (internal region) blocking peptide

别名:

MOB kinase activator 1B , MATS2 , MOB4A , MOBKL1A

反应种属:

Human

宿主来源:

Mouse

实验应用:

FCM, IHC-P, WB

同种型:

IgG2a

免疫原:

Full length human recombinant protein of human MOBKL1A(NP_775739) produced in HEK293T cell.

克隆性:

Monoclonal

克隆号:

1H2

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.

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