深圳欣博盛生物科技有限公司 a1

Si5-N14
货号:42520-1 mg 规格:1 mg 目录价:¥817.4
货号:42520-10 mg 规格:10 mg 目录价:¥5681.6
货号:42520-5 mg 规格:5 mg 目录价:¥3242.8
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Si5-N14
产品描述:
A siloxane-incorporated ionizable cationic lipidoid; has been used in the generation of LNPs for the delivery of mRNA and sgRNA in vitro and in vivo; LNPs containing Si5-N14 and encapsulating a luciferase mRNA reporter exhibit increased cellular uptake via micropinocytosis and lipid raft-mediated endocytosis pathways and endosomal escape compared with LNPs containing non-siloxane-incorporated lipids in iMVECs; LNPs containing Si5-N14 and encapsulating a luciferase mRNA reporter selectively accumulate in the lungs in mice; Si5-N14 LNPs encapsulating Cas9 mRNA and GFP sgRNA reduce GFP levels in lung MVECs without increasing BALF cytokine levels in a transgenic GFP mouse model
保存温度:
-20
运输温度:
-20
预期分子量:
1318.31344
产品形式:
A solution in ethanol
有效期:
730
纯度:
≥95%
CAS号:
3006860-57-4
分子式:
C78H160N6O5Si2
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