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折扣/货期| 货号：AG-CN2-0539-M005 | 规格：5 mg | 目录价：￥720 |
| 货号：AG-CN2-0539-M025 | 规格：25 mg | 目录价：￥2160 |
| 货号：AG-CN2-0539-M100 | 规格：100 mg | 目录价：￥4560 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Simvastatin . sodium salt
别名:
MK-733; Synvinolin; BRN 4768037
产品描述:
Synthetic analog of Lovastatin (Prod. No. AG-CN2-0051 http://www.adipogen.com/ag-cn2-0051/lovastatin.html ). Water-soluble carboxylate form of Simvastatin (Prod.No. AG-CN2-0052 https://adipogen.com/ag-cn2-0052-simvastatin.html ). Potent competitive HMG-CoA reductase inhibitor [1]. Anti-hypercholesterolemic agent [1]. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids [1, 2]. Inhibits the isoprenylation of Ras and Rho family GTPases [2]. Smooth muscle cell proliferation inhibitor [3]. Anti-adhesive, immunomodulatory and anti-inflammatory compound [4, 7, 10]. Proteasome modulator [5]. Stimulates bone formation [6]. Apoptosis inducer [8]. Anticancer compound [8, 9]. Increases cellular resistance to anticancer agents such as doxorubicin and etoposides (Prod. No. AG-CR1-3572 http://www.adipogen.com/ag-cr1-3572/etoposide.html ) [9]. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection [11, 12]. Anti-hypertensive agent [13]. Suppresses TNF-induced NF-kappaB activation [14].
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
435.6 . 23.0
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
101314-97-0
分子式:
C25H39O6 . Na
溶解度:
Soluble in water (30mg/ml). Soluble in DMSO, ethanol or DMF (all 10mg/ml).
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