| 货号:AG-CP3-0002-M001 | 规格:1 mg | 目录价:¥1980 |
| 货号:AG-CP3-0002-M005 | 规格:5 mg | 目录价:¥8280 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Z-VAD-FMK (Cell permeable)
别名:
Z-VAD(OMe)-FMK; Z-Val-Ala-DL-Asp(OMe)-FMK; pan-Caspase Inhibitor
产品描述:
Cell permeable, non-selective broad-spectrum caspase inhibitor [1, 3, 7, 8]. Binds irreversibly to the catalytic site of caspase proteases [1]. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability [1]. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction [2-4, 6, 9]. Decreases proteasome activity [5]. Potent inhibitor of caspase-1 activation in NLRP3/NALP3-induced cells [10]. Used in apoptosis and inflammasome studies.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
467.5
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
187389-52-2 and 634911-81-2
分子式:
C22H30FN3O7
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