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折扣/货期| 货号：RQ6325 | 规格：100 ug | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SMAD2 Antibody
产品描述:
Smad2 (Mothers against decapentaplegic homolog 2), also known as MADR2, MADH2, SMAD family member 2 or SMAD2, is a protein that in humans is encoded by the SMAD2 gene. MAD homolog 2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. Eppert et al. mapped the MADR2 gene close to DPC4 at 18q21, a region which is frequently deleted in colorectal cancers. Riggins et al. mapped the human MADH2 gene to 18q21. Nakao et al. refined the localization of the SMAD2 gene to 18q21.1, approximately 3 Mb proximal to DPC4, by fluorescence in situ hybridization. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P, FACS
同种型:
Mouse IgG1
免疫原:
Recombinant human protein (amino acids E83-Q264) was used as the immunogen for the SMAD2 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
3C4
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the SMAD2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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