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折扣/货期| 货号：40645-1 mg | 规格：1 mg | 目录价：￥375 |
| 货号：40645-10 mg | 规格：10 mg | 目录价：￥2211 |
| 货号：40645-25 mg | 规格：25 mg | 目录价：￥3685 |
| 货号：40645-5 mg | 规格：5 mg | 目录价：￥1394 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SMIP004
别名:
SKP2 E3 Ligase Inhibitor II|S-phase Kinase-associated Protein 2 E3 Ligase Inhibitor 11
产品描述:
An SKP2 inhibitor; reduces SKP2 levels and induces the accumulation of p27Kip1 and p21Cip21 in LNCaP-S14 cells at 40 µM; cytotoxic to LNCaP-S14 cells (IC50 = 1.09 µM) but not non-cancerous IMR-90 human fibroblasts; also targets cyclin D1 for proteasomal degradation, as well as induces the unfolded protein response, oxidative stress, apoptosis, and cell cycle arrest at the G1 phase in LNCaP-S14 cells; reduces immobility time in the forced swim test and tail suspension test, as well as increases the preference for sucrose in the sucrose preference test, in a mouse model of chronic unpredictable stress-induced depression at 2 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
205.2961
产品形式:
A solid
纯度:
≥98%
CAS号:
143360-00-3
分子式:
C13H19NO
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