SPARC Antibody / Secreted protein acidic and rich in cysteine / Osteonectin
| 货号:V5796-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V5796-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
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产品名称:
SPARC Antibody / Secreted protein acidic and rich in cysteine / Osteonectin
产品描述:
SPARC (for secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. It is identical to osteonectin, a protein important to bone calcification that is highly conserved between species. SPARC, which can be selectively expressed by the endothelium in response to certain types of injury, induces rounding in adherent endothelial cells in vitro. It regulates endothelial barrier function through F-Actin-dependent changes in cell shape, coincident with the appearance of intercellular gaps, which provide a paracellular pathway for extravasation of macromolecules.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
Mouse IgG1, kappa
免疫原:
A portion of amino acids 1-200 from human SPARC protein was used as the immunogen for the SPARC antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
OSTN/3761
纯化方式:
Protein G affinity
保存温度:
Aliquot the SPARC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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