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折扣/货期| 货号：GTX11184 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Spectrin antibody [SB-SP1]
别名:
spectrin alpha, erythrocytic 1 , EL2 , HPP , HS3 , SPH3 , SPTA
反应种属:
Human
宿主来源:
Mouse
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody reacts specifically with the α and β chains of human erythrocyte spectrin.
同种型:
IgG1
免疫原:
human erythrocyte spectrin.
克隆性:
Monoclonal
克隆号:
SB-SP1
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
280
产品形式:
Liquid
存储溶液:
Ascites, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Spectrin is a major constituent of the erythrocyte skeleton accounting for 25% of the total membrane protein and 75% of the cytoskeletal mass. It is associated with the cytoplasmic surface of the membrane by attachment to ankyrin, a peripheral membrane protein. The membrane skeleton influences several cellular properties such as cell shape, restriction of mobility of the integral membrane protein exposed at the cell surface and transmembrane movement of phospholipids and cholesterol. On SDS PAGE gels erythrocyte spectrin appears as two bands referred to as alpha (240kD) and beta (220kD). While the simplest form of spectrin in solution is an alpha-beta heterodimer, spectrin can undergo self-association in various conditions to form a tetramer of alpha2-beta2. In recent years a large number of spectrin-like molecules have been found in non-erythroid cells. These proteins are known by such different names as fodrin, CBP I, calspectin and TW 260/240.
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