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折扣/货期| 货号：GTX02717 | 规格：100μg | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SPTBN2 antibody [SPTBN2/2887R]
别名:
spectrin beta, non-erythrocytic 2 , GTRAP41 , SCA5 , SCAR14
反应种属:
Human
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
Recombinant human SPTBN2 fragment (aa356-475)
克隆性:
Monoclonal
克隆号:
SPTBN2/2887R
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
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