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折扣/货期| 货号：GTX30467 | 规格：100μl | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SR-BI antibody
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, IHC-Fr, IHC-P, IP, Neutralizing/Inhibition, WB
同种型:
IgG
免疫原:
Adenovirus encoding mouse SR-BI. [UniProt# Q61009]
克隆性:
Polyclonal
克隆号:
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Serum, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
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