| 货号:25-469 | 规格:100 ul | 目录价:¥9108.45 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
STAT5B Antibody
别名:
STAT5B, STAT5
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB
克隆性:
Polyclonal
纯化方式:
Antibody is purified by peptide affinity chromatography method.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STAT5B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产地:
美国
生产商:
Prosci
功能与背景:
The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Accession #:
NP_036580

官网链接
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