官网链接
折扣/货期| 货号：AG-40T-0004-3020 | 规格：3 x 20 ug | 目录价：￥11520 |
| 货号：AG-40T-0004-C020 | 规格：20 ug | 目录价：￥4800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SuperKillerTRAIL, Soluble (mouse) (rec.) MultiPack
别名:
TRAIL; Apo-2L; TNFSF10; CD253
产品描述:
TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors: TRAIL-R1 (DR4; Apo2;CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A;TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1;LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2; TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerized TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducing the formation of the so-called multiprotein death-inducing signaling complex (DISC).
宿主来源:
E. coli
靶标/特异性:
Binds to mouse and less potently to human TRAIL receptors.
产品浓度:
0.5mg/ml
保存温度:
-20°C
运输温度:
DI
预期分子量:
~24kDa
产品形式:
liquid
存储溶液:
Liquid. In 20mM HEPES, pH 7.4, 300mM NaCl, 0.01% Tween 20, 1% sucrose, 1mM DTT.
有效期:
Once thawed it is recommended to prepare appropriate aliquots and to store them at -80°C. , Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces apoptosis at concentrations of >10ng/ml as tested on human tumor cells. This effect can be efficiently blocked by recombinant mouse TRAIL receptors. This protein does not require a cross-linker (enhancer) for its potent biological activity.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
促销活动
精品推荐
相关产品推荐
PLXDC2 (mouse) (rec.) (His)
货号：AG-40B-0271-C050
Ubiquitin Activating Enzyme E1 [UBA1; UBE1] (human) (rec.) (untagged)
货号：SBB-CE0011-C050
UBE2D3 [UbcH5c ] (human) (rec.) (untagged)
货号：SBB-CE0019-C100
UBE2L3 [UbcH7] (human) (rec.) (untagged)
货号：SBB-CE0020-C100
UBE2D1 [UbcH5a] (human) (rec.) (untagged)
货号：SBB-CE0021-C100
UBE2K [UbcH1, E2-25K] (human) (rec.) (His)
货号：SBB-CE0022-C100
