深圳欣博盛生物科技有限公司 a1

TAB3 Antibody
品牌:ProSci LLC
货号:3391-0.02 mg 规格:0.02 mg 目录价:¥1345.5
货号:3391-0.1 mg 规格:0.1 mg 目录价:¥6084
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TAB3 Antibody
别名:
TAB3 Antibody: NAP1, MAP3K7IP3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, TAB-3
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA,IHC-P
靶标/特异性:
TAB3 antibody is human specific. TAB3 antibody is predicted not to cross-react with other TAB proteins.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
TAB3 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
TAB3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
TAB3 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
TAB3 Antibody: TAB3 functions in the NF-kappaB signal transduction pathway. It and the similar and functionally redundant protein TAB2, form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.
Accession #:
NP_690000
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