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折扣/货期| 货号：AG-40B-0079-3050 | 规格：3 x 50 ug | 目录价：￥6720 |
| 货号：AG-40B-0079-C050 | 规格：50 ug | 目录价：￥3360 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TACI (human):Fc (human) (rec.)
别名:
TNFRSF 13B; Tumor Necrosis Factor Receptor Superfamily Member 13B; Transmembrane Activator and CAML interactor; CD267
产品描述:
B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL) and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor (BAFF) of ligands and a proliferation inducing ligand (APRIL), which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils. TNFRSF13B, the gene, which encodes TACI is mutated in nearly 10% of patients with common variable immune deficiency (CVID), an antibody deficiency syndrome characterized by loss of memory B cells and plasma cells.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds to human and mouse BAFF and APRIL.
产品浓度:
1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~45kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
Inhibits BAFF and APRIL activity.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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