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折扣/货期| 货号：22208-10 mg | 规格：10 mg | 目录价：￥1997 |
| 货号：22208-25 mg | 规格：25 mg | 目录价：￥3136 |
| 货号：22208-5 mg | 规格：5 mg | 目录价：￥1273 |
| 货号：22208-50 mg | 规格：50 mg | 目录价：￥4958 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TAK-063
产品描述:
A potent inhibitor of PDE10A (IC50 = 0.3 nM); >15,000-fold selective for PDE10A over other PDEs and exhibits <50% inhibition at 91 receptors, ion channels, and enzymes at a concentration of 10 μM; increases cAMP and cGMP levels by 1.3- and 2.14-fold, respectively, in the striatum of mice when administered at a dose of 0.3 mg/kg; reverses PCP-induced hyperlocomotion (MED = 0.3 mg/kg, p.o.) in wild-type mice but has no effect in PDE10A knockout mice at doses up to 1 mg/kg; reverses (+)-MK-801-induced hyperlocomotion (MED = 0.1 mg/kg, p.o.) but has no effect on plasma prolactin or glucose levels in rats
保存温度:
-20
运输温度:
-20
预期分子量:
428.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1238697-26-1
分子式:
C23H17FN6O2
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